Inclusion Criteria:
* 1\. Females who are at least 18 years old and less than 46 years old (i.e., 18 to 45 years old).
2\. Subjects sign a written informed consent form (ICF) to participate in the trial voluntarily, and are able to fully understand the trial procedures, the risks of participating in the trial, and the alternative interventions available to them if they do not participate in the trial.
3\. Be able to read, understand and complete the diary/contact card. 4. Be in good health as judged by the history interview and physical examination.
5\. Have a history of sexual behavior prior to enrollment. 6.\*Avoid sexual intercourse (including same-sex or opposite-sex anal, vaginal, or genital/genital contact) and avoid vaginal douching, vaginal cleansing, or the use of vaginal medications or preparations for 48 hours prior to any visit that includes sample collection.
7\. Subjects who are not breastfeeding at the time of enrollment and who have used effective contraception from the time of their last menstrual period until enrollment in the study, and who understand and agree to use effective contraception from the first day of enrollment until 1 month after the last vaccination.
8.\* Those with axillary body temperature \<37.3°C on the day of enrollment. 9. Note: Subjects who do not meet the \*enrollment criteria are allowed to be screened again, but the enrollment criteria still need to be confirmed again at the time of enrollment.
Exclusion Criteria:
* 1\. \*Positive urine pregnancy test or pregnancy (including ectopic pregnancy) that has ended less than 6 weeks ago.
2\. Prior vaccination with a marketed HPV vaccine or already enrolled in a clinical trial of another HPV vaccine or have plans to receive a non-study HPV vaccine during the study period.
3\. Have a prior history of cervical cancer screening abnormalities or lesions \[including HPV DNA positivity, squamous intraepithelial lesions (SIL) or atypical squamous cells of undetermined significance (ASC-US), atypical squamous epithelial cells-without the exception of high grade squamous intraepithelial lesions (ASC-H), atypical glandular cells (AGC), or have cervical intraepithelial neoplasia (CIN), adenocarcinoma in situ (AIS) or cervical cancer\]. ) or cervical cancer, etc.\].
4\. Previous or current anal or genital disease (e.g. vulvar intraepithelial neoplasia, vaginal intraepithelial neoplasia, genital warts, vulvar, vaginal, and anal cancers) 5. Previous total hysterectomy or pelvic radiation therapy or severe developmental abnormalities of the cervix/vagina.
6\. History of drug or alcohol abuse or dependence in the last year. 7. Have hypertension or diabetes mellitus that cannot be controlled and stabilized with pharmacological interventions.
8\. Subjects with a history of severe allergic reactions to any vaccine or medication requiring medical intervention (e.g., anaphylaxis, anaphylactic laryngeal edema, anaphylactic purpura, thrombocytopenic purpura, localized anaphylactic necrotic reaction \[Arthus reaction\], etc.).
9\. Currently immunocompromised or diagnosed with congenital or acquired immunodeficiency, HIV infection, lymphoma, tuberculosis, leukemia, systemic lupus erythematosus (SLE), rheumatoid arthritis (JRA), inflammatory bowel disease, or other autoimmune disease.
10\. Previous splenectomy or impaired splenic function. 11. Currently receiving or have received the following immunosuppressive therapies in the last year: radiation therapy, cyclophosphamide, imidazathioprine, methotrexate, as well as chemotherapy, cyclosporine, leflunomide, tumor necrosis factor-alpha antagonists, monoclonal antibody therapies, intravenous gammaglobulin, anti-lymphocytic serums, or other therapies that are known to interfere with immunity 12. Current treatment with systemic corticosteroids or 2 or more courses of high-dose glucocorticoids lasting one week in the year prior to enrollment. The use of nasal inhaled glucocorticoids or topical short-term topical application on the skin may not be excluded.
13\. Receipt of any immunoglobulin product or blood product within 3 months prior to vaccination, or planning to receive such similar products during the study period from Day 1 to Month 7.
14\. \* Inactivated/recombinant/nucleic acid vaccine, etc. (non-attenuated) within 14 days prior to vaccination or live attenuated vaccine within 28 days prior to vaccination.
15\. Contraindication to intramuscular injection such as thrombocytopenia or other coagulation disorders.
16\. \*Blood donation within 1 week prior to vaccination or planning to donate blood between Day 1 and Month 7 of study participation.
17\. Participation in other experimental clinical studies or studies with unregistered products (drugs or vaccines) or collection of cervical specimens within 3 months prior to vaccination.
18\. Inability to follow trial procedures or planned relocation during the study.
19\. \*Fever (axillary temperature ≥37.3°C) within 3 days prior to vaccination or any acute illness requiring systemic antibiotic or antiviral therapy within the past 5 days.
20\. \*Clinical signs/symptoms suggestive of acute reproductive tract infection (e.g. acute vulvovaginitis/vaginitis/cervicitis \[including purulent cervicitis\], etc.) during gynecological examination.
21\. \* Being in the menstrual period (sampling should be done 2 days after the end of menstruation).
22\. Have an active neurological/psychiatric/psychological disorder that prevents compliance with the study requirements.
23\. Have other abnormalities, conditions that may confound the results of the study, or conditions that are not in the best interest of the subject and may be excluded as determined by the investigator.
24\. Note: Subjects who meet \*exclusion criteria are allowed to be re-screened, but enrollment will still require re-confirmation of inclusion criteria.
