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ENROLLING BY INVITATION
NCT06042621

A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)

Sponsor: University of Wisconsin, Madison

View on ClinicalTrials.gov

Summary

The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care unit (ICU). A time-limited trial is a plan made together by medical teams, patients with critical illness (if they can take part), and their families or other important people helping to make their healthcare decisions. A time-limited trial starts with a discussion of the patient's goals and wishes. Then, a plan is made to use ICU treatments for a set period of time to give the patient the chance to recover. After this time, the patient's response to treatment will be reviewed to help guide what to do next. Medical teams consider this kind of plan when it is not clear if a patient can recover to a quality of life that is acceptable to them. With a time-limited trial, patients, families, and medical teams experience this uncertainty together. The main goal of this study is to find the best way to use TLTs for patients in the ICU who have trouble breathing and need mechanical ventilation to help them breathe. The hypothesis is that optimal time-limited trial delivery will reduce the time patients with acute respiratory failure spend in the ICU and will improve the intensive care unit experiences for their families and clinicians.

Official title: Optimizing Time-Limited Trials of Mechanical Ventilation in Acute Respiratory Failure (The TIME Study): A Mixed Methods Observational Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

7818

Start Date

2024-01-17

Completion Date

2028-03

Last Updated

2026-02-05

Healthy Volunteers

Yes

Locations (5)

Northwestern Memorial Hospital

Chicago, Illinois, United States

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, United States

UnityPoint Health - Meriter Hospital

Madison, Wisconsin, United States

University of Wisconsin-Madison

Madison, Wisconsin, United States