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Revitalization of Traumatized Immature Permanent Teeth
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
This study aims to assess the hypothesis that revitalization of teeth without (a)symptomatic apical periodontitis have a more favourable outcome in terms of further root development, periapical bone healing, maintaining/regaining pulp sensitivity and survival, than teeth with (a)symptomatic apical periodontitis.
Official title: Revitalization of Immature Permanent Teeth With or Without Apical Periodontitis Post Trauma: a European Multicenter Cohort Study
Key Details
Gender
All
Age Range
6 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
72
Start Date
2023-10-01
Completion Date
2030-09-01
Last Updated
2024-07-01
Healthy Volunteers
Yes
Conditions
Interventions
revitalization
The main idea behind revitalization is to firstly disinfect the root canal and subsequently attract or transplant mesenchymal stem cells from the (remaining) dental pulp and apical papilla (in case of immature permanent teeth) into the root canal. More specifically, this therapy is not based on mechanical and (aggressive) chemical debridement as in conventional root canal treatment but is supported by the pillars of tissue engineering: stem cells, growth factors and a scaffold .
Locations (1)
Ghent University
Ghent, Belgium