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Early Diagnosis of Breast Cancer-related Lymphedema
Sponsor: Kaohsiung Veterans General Hospital.
Summary
This study will conduct clinical trials to explore the mechanisms behind the development of upper limb lymphedema following breast cancer surgery. The investigators will recruit patients who have undergone breast cancer surgery and utilize Indocyanine Green (ICG) lymphography and Lymphoscintigraphy to identify the locations of lymphatic blockages. Shear Wave Elastography (SWE) will be used to detect changes in tissue limb compliance. DXA body composition analysis will measure the differences in the composition ratios between edematous and normal limbs. In addition, diffusion correlation spectrometry will be employed to monitor changes in deep tissue blood flow, complemented by continuous measurements of limb circumference and other physiological parameters. The study aims to explore the interrelationships among lymphatic circulation, limb circumference, tissue compliance, and tissue blood flow rates.
Key Details
Gender
FEMALE
Age Range
20 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2022-10-24
Completion Date
2026-12-31
Last Updated
2025-06-11
Healthy Volunteers
No
Conditions
Interventions
lymphoscintigraphy
lymphoscintigraphy
circumference measurement
circumference measurement
sonography
B-mode sono and elastography
DXA body composition analysis
DXA body composition analysis
Locations (1)
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan