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RECRUITING
NCT06046365

Early Diagnosis of Breast Cancer-related Lymphedema

Sponsor: Kaohsiung Veterans General Hospital.

View on ClinicalTrials.gov

Summary

This study will conduct clinical trials to explore the mechanisms behind the development of upper limb lymphedema following breast cancer surgery. The investigators will recruit patients who have undergone breast cancer surgery and utilize Indocyanine Green (ICG) lymphography and Lymphoscintigraphy to identify the locations of lymphatic blockages. Shear Wave Elastography (SWE) will be used to detect changes in tissue limb compliance. DXA body composition analysis will measure the differences in the composition ratios between edematous and normal limbs. In addition, diffusion correlation spectrometry will be employed to monitor changes in deep tissue blood flow, complemented by continuous measurements of limb circumference and other physiological parameters. The study aims to explore the interrelationships among lymphatic circulation, limb circumference, tissue compliance, and tissue blood flow rates.

Key Details

Gender

FEMALE

Age Range

20 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2022-10-24

Completion Date

2026-12-31

Last Updated

2025-06-11

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

lymphoscintigraphy

lymphoscintigraphy

DIAGNOSTIC_TEST

circumference measurement

circumference measurement

DIAGNOSTIC_TEST

sonography

B-mode sono and elastography

DIAGNOSTIC_TEST

DXA body composition analysis

DXA body composition analysis

Locations (1)

Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan