Clinical Research Directory

The eligibility criteria for this feasibility study are designed to select participants who will provide valuable insights into myocardial metabolism using HP-13C MRI in various contexts related to ischemic heart failure. These criteria aim to ensure that the study population is diverse and representative of the patient groups under investigation. Inclusion/Exclusion Criteria: * Age range: 20 to 80 years * Sex: Random allocation * Left ventricular ejection fraction (LVEF): * Preoperative patients with LVEF \< 0.35 * Healthy subjects with LVEF \> 0.50 * Clinical history: * Previous myocardial infarction (MI): Excluded for healthy subjects, included for preoperative patients. * Diabetes mellitus: Excluded for all participants. * Hypertension: Included for all participants * Mean blood pressure: Systolic \< 140 mm Hg and Diastolic \< 90 mm Hg for all participants * Mean heart rate: 78 beats/min for all participants * Current smoker status: Included but will be reported. * Medication use within 24 hours: Use will be reported. * Coronary artery bypass surgery history: Excluded for healthy subjects, included for preoperative patients. * Infarct type and location: Excluded for healthy subjects, included for preoperative patients with various Q-wave infarct types and locations. * Number of diseased coronary vessels: Excluded for healthy subjects, included for preoperative patients with at least one diseased vessel. * Additional medical history and clinical data: Variations in data availability are expected based on the practices of referring physicians and will be documented.