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The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
Sponsor: Singapore Eye Research Institute
Summary
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery. The secondary aim is to identity the characteristics of patients who will benefit the most with the use of ripasudil based on the test results obtained from this study.
Official title: The Effects of Ripasudil in Patients With Fuchs Endothelial Corneal Dystrophy Undergoing Femtosecond Laser Assisted Cataract Surgery
Key Details
Gender
All
Age Range
50 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-03-01
Completion Date
2025-07
Last Updated
2025-01-29
Healthy Volunteers
No
Conditions
Interventions
Ripasudil
Glanatec Ophthalmic Solution 0.4% W/V with ripasudil hydrochloride hydrate as active ingredient is currently being used by patients with ocular hypertension or open-angle glaucoma. Inhibition of Rho kinase to facilitate aqueous outflow from the conventional outflow pathway via the trabecular meshwork and Schlemm's canal has been suggested as the IOP-lowering mechanism of action by ripasudil.
Placebo
Saline eye drops
Locations (1)
Singapore National Eye Centre
Singapore, Singapore, Singapore