Clinical Research Directory

Inclusion Criteria: * Patients after cardiac arrest admitted to the ICU for treatment with sedation, TTM and mechanical ventilation. * Age 18 years or older. * Continuous EEG measurement started within 12 hours after cardiac arrest. * Favourable EEG pattern within 12 hours after arrest, defined as a continuous background pattern (NVN, 2019; Ruijter et al., 2019). * Possibility to stop sedative treatment within three hours after identification of a favourable EEG pattern. * Written informed consent (deferred). Exclusion Criteria: * A known history of another medical condition with limited life expectancy (\<6 months). * Any progressive brain illness, such as a brain tumour or neurodegenerative disease. * Pre-admission Glasgow Outcome Scale Extended score of 4 or lower. * Reason other than neurological condition to continue sedation and/or ventilation. * Follow-up impossible due to logistic reasons.