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CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations
Sponsor: Assistance Publique - Hôpitaux de Paris
Summary
This research focuses on behavioral sensitization (BS) a specific behavioural disturbance in crack-cocaine addiction. The primary objective is to observe whether BS can be demonstrated in an ecological setting in crack dependent users by continuous actimetry for 3 weeks. It is planned to include 20 persons with a current crack-cocaine addiction with a preferential use of rapid administration route (intravenous or smoke), in a care institution: Fernand Widal Hospital. In the proposed research, the investigators will assess the movements of crack-cocaine dependent users in relation to consumption. They will have to wear continuously for 3 weeks an actimeter. They will also have 3 blood tests trying to identify biomarkers of BS.
Official title: Descriptive Study of Observed Behavioural Awareness and Patients Expectations of Treatment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-03-04
Completion Date
2026-03-04
Last Updated
2026-01-15
Healthy Volunteers
No
Conditions
Interventions
Observation of behavior and search of biomarkers with 3 blood tests.3 weeks wearing an actimeter
In the form of a small watch, which collects the level of motor activity throughout the day and night. Patients will be asked to indicate each moment of crack-cocaine use by pressing the button in the center of the watch. We want to know if certain uses lead to more behavioral problems (especially after periods of cessation).
3 blood tests
We will try to identify biomarkers of BS: blood proteins, genetic markers passed on by your parents, or the expression of proteins in particular situations
Locations (2)
Centre 001_Hôpital Fernand Widal
Paris, France
Hôpital Fernand Widal
Paris, France