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Spatial-Motor Stroke-Rehab Study
Sponsor: Emory University
Summary
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
Official title: Novel Spatial-Motor Approaches to Improve Spatial Neglect and Walking Deficits Post-Stroke
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2023-04-11
Completion Date
2026-03
Last Updated
2025-10-16
Healthy Volunteers
Yes
Conditions
Interventions
Prism adaptation therapy (PAT) + Electrical stimulation (E-stim)
PAT requires one to wear prism lenses while making arm-reaching movements toward visual targets. For treating left-sided neglect, a person wears the prism lenses that shift the visual field, including the images of the target and of one's own reaching arm, certain degrees to the right depending on the diopter of the lens (e.g., the 20-diopter lens shifts the visual field by 11.4 degrees). The visual system adapts over the repetitive practice of the arm reaching toward the target. The person eventually achieves success with a leftward movement reaching the actual target. Electrical stimulation (E-stim) involves parameters and settings commonly used in clinical practice as well as research for pain relief and other applications, commonly referred to as transcutaneous electrical nerve stimulation (TENS). TENS and E-stim are delivered using FDA-approved, commercially available portable clinical transcutaneous electrical stimulators (e.g. Empi TENS Unit).
Prism adaptation therapy (PAT) + Sham Stimulator
Participants in the PAT with sham stim condition group will receive sham electrical stimulation treatment (electrodes will be attached but the stimulator will not be turned on) to the left upper limb with the same placement of electrodes while undergoing PAT.
Gait Training
After PAT, participants will complete multiple 30-seconds to 4-minute bouts of walking on the treadmill or overground at speeds ranging from self-selected to fast speeds (faster than comfortable self-selected speed), with rest breaks between bouts.
Locations (3)
Emory Rehabilitation Hospital
Atlanta, Georgia, United States
Emory University Hospital (EUH)
Atlanta, Georgia, United States
Executive Park
Atlanta, Georgia, United States