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Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
Sponsor: Montefiore Medical Center
Summary
This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy (including intubation) when compared to using a standard mode of non-invasive ventilation. Neurally-Adjusted Ventilatory Assistance (NAVA) has been shown to result in greater synchrony then the standard mode of non-invasive ventilation. The study team hypothesizes that this improved synchrony can result in important clinical improvements when NAVA is used to treat children with bronchiolitis.
Official title: Comparison of Conventional Non-Invasive Ventilation and Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Ventilation for the Treatment of Bronchiolitis
Key Details
Gender
All
Age Range
0 Years - 2 Years
Study Type
INTERVENTIONAL
Enrollment
130
Start Date
2023-12-18
Completion Date
2027-03
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Standard Non-Invasive Mechanical Servo Ventilation
The active comparator arm will utilize a standard non-invasive mode to provide ventilation support
Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
The experimental arm will utilize a NAVA mode to provide non-invasive ventilation support
Locations (1)
Children's Hospital at Montefiore
The Bronx, New York, United States