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ACTIVE NOT RECRUITING
NCT06053775
NA

Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)

Sponsor: University of Santiago de Compostela

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive Training (OCT) to treat depressive symptomatology and cognitive decline associated with breast cancer. The main questions aims to be answered are: * To analyze the efficacy and feasibility of the intervention to treat depressive symptomatology. * To analyze the efficacy and feasibility of the intervention to treat cognitive decline. * To evaluate the medium and long-term effects (1, 3 and 6 months) of intervention. An OCT program and a portable wireless tDCS/tACS system will be used to perform the intervention at home. Patients will be divided into four treatment groups, depending on whether they will receive the OCT applied independently or combined with tDCS/tACS active or sham. In addition, saliva samples will be collected to identify bomarkers predictive of treatment efficacy.

Official title: Intervention With Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Associated With Breast Cancer (ONCODEP)

Key Details

Gender

FEMALE

Age Range

30 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

82

Start Date

2023-09-27

Completion Date

2025-09

Last Updated

2025-07-20

Healthy Volunteers

No

Interventions

DEVICE

Transcranial Direct Current Stimulation

tDCS+OCT

DEVICE

Transcranial Alternating Current Stimulation

tACS+OCT

DEVICE

tES sham

tES sham + OCT

DEVICE

Online Cognitive Training

OCT

Locations (2)

University of Santiago de Compostela

Santiago de Compostela, A Coruña, Spain

Fundación Biomédica Galicia Sur

Vigo, Pontevedra, Spain