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Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
Sponsor: University of Santiago de Compostela
Summary
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive Training (OCT) to treat depressive symptomatology and cognitive decline associated with breast cancer. The main questions aims to be answered are: * To analyze the efficacy and feasibility of the intervention to treat depressive symptomatology. * To analyze the efficacy and feasibility of the intervention to treat cognitive decline. * To evaluate the medium and long-term effects (1, 3 and 6 months) of intervention. An OCT program and a portable wireless tDCS/tACS system will be used to perform the intervention at home. Patients will be divided into four treatment groups, depending on whether they will receive the OCT applied independently or combined with tDCS/tACS active or sham. In addition, saliva samples will be collected to identify bomarkers predictive of treatment efficacy.
Official title: Intervention With Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Associated With Breast Cancer (ONCODEP)
Key Details
Gender
FEMALE
Age Range
30 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
82
Start Date
2023-09-27
Completion Date
2025-09
Last Updated
2025-07-20
Healthy Volunteers
No
Conditions
Interventions
Transcranial Direct Current Stimulation
tDCS+OCT
Transcranial Alternating Current Stimulation
tACS+OCT
tES sham
tES sham + OCT
Online Cognitive Training
OCT
Locations (2)
University of Santiago de Compostela
Santiago de Compostela, A Coruña, Spain
Fundación Biomédica Galicia Sur
Vigo, Pontevedra, Spain