Clinical Research Directory

Browse clinical research sites, groups, and studies.

Sites Groups Studies

Back to Studies

ENROLLING BY INVITATION

NCT06055712

PHASE4

Antibiotic Prophylaxis in Pediatric Open Fractures

Sponsor: St. Louis University

View on ClinicalTrials.gov

Summary

This research will involve a prospective study on infection rates after grade 1 or 2 open fractures in the skeletally immature pediatric population. There will be 3 arms: one dose intravenous cefazolin, 24 hours intravenous cefazolin, and 24 hours intravenous cefazolin plus 5 days of oral cephalexin.

Key Details

Gender

All

Age Range

0 Years - 17 Years

Study Type

INTERVENTIONAL

Enrollment

800

Start Date

2023-09-11

Completion Date

2034-01

Last Updated

2025-10-20

Healthy Volunteers

Conditions

Fractures, Open Infections

Interventions

DRUG

Cefazolin

Intravenous dose(s).

DRUG

Cephalexin

Five days oral.

Locations (1)

Saint Louis University

St Louis, Missouri, United States