Clinical Research Directory

Key Inclusion Criteria: 1. Must have measurable disease according to RECIST v1.1. 2. Eastern Cooperative Oncology Group (ECOG) performance status score of 0-1. 3. Acceptable organ and bone marrow function. 4. Participant must have a life expectancy of at least 3 months. Key Exclusion Criteria: 1. Has clinically significant toxicities from previous anticancer therapies. 2. Has rapidly progressing disease. 3. Has a history of noninfectious pneumonitis/interstitial lung disease. 4. Has a history of liver disease. 5. Has had an allogeneic tissue/solid organ transplant or autologous or allogeneic bone marrow transplant, or stem cell rescue within 3 months prior to the first dose of GEN1042. 6. Has any history of intracerebral arteriovenous malformation, cerebral aneurysm, or progressive brain metastases or stroke. 7. Has had major surgery within 4 weeks before Screening. NOTE: Other protocol defined Inclusion/Exclusion criteria may apply.