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The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect
Sponsor: The George Institute
Summary
CAPTIVATE is an international, multi-centre, Phase III, adaptive, platform, randomised controlled trial in people with chronic kidney disease (CKD). CAPTIVATE aims to find the best treatment, or combination of treatments, that slow the progression of CKD so that fewer people develop kidney failure. CAPTIVATE provides a research platform that allows many treatment-related questions to be answered within a common trial set-up.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2024-09-04
Completion Date
2029-03-31
Last Updated
2026-04-01
Healthy Volunteers
No
Conditions
Interventions
Finerenone
Finerenone 10mg or 20mg tablets, oral, once daily
Placebo Finerenone
Finerenone matched placebo tablets, oral, once daily
Locations (43)
The Canberra Hospital
Garran, Australian Capital Territory, Australia
Nepean Blue Mountains Local Health District
Kingswood, New South Wales, Australia
St George Hospital
Kogarah, New South Wales, Australia
John Hunter Hospital
New Lambton Heights, New South Wales, Australia
Westmead Hospital
Westmead, New South Wales, Australia
Sunshine Coast Hospital and Health Service
Birtinya, Queensland, Australia
Townsville University Hospital
Douglas, Queensland, Australia
West Moreton Hospital & Health Service
Ipswich, Queensland, Australia
Gold Coast Hospital and Health Service
Southport, Queensland, Australia
Royal Adelaide
Adelaide, South Australia, Australia
Lyell McEwin Hospital
Elizabeth Vale, South Australia, Australia
Austin Health
Heidelberg, Victoria, Australia
South Metropolitan Health Service, Fiona Stanley Hospital
Murdoch, Western Australia, Australia
Gitam Institute of Medical Sciences and Research
Visakhapatnam, Andhra Pradesh, India
Patna Medical College and Hospital
Patna, Bihar, India
DKS Super Speciality Hospital, Raipur
Raipur, Chhattisgarh, India
Mysore Medical College
Dehradun, Dehradun, India
GCS Medical College, Hospital & Research Centre
Ahmedabad, Gujarat, India
Father Muller Medical College Hospital
Mangaluru, Karnataka, India
Dr Moopen's Medical College
Meppādi, Kerala, India
CARE-CHL Hospital
Indore, Madhya Pradesh, India
Medway Hospital
Chennai, Tamil Nadu, India
Yashoda Hospital Hitec City
Hyderabad, Telangana, India
Apollo Hospitals
Hyderabad, Telangana, India
Charak Hospital and Research Centre
Lucknow, Uttar Pradesh, India
Shri Guru Ram Rai Medical College and Shri Mahant Indiresh Hospital
Dehradun, Uttarakhand, India
Fortis Hospital
Kolkata, West Bengal, India
North Bengal Medical College & Hospital
Siliguri, West Bengal, India
Max Superspeciality Hospital, Dehradun
Dehradun, India
Health New Zealand, Te Whatu Ora Te Matau a Maui, Hawke's Bay Hospital
Hastings, Hawkes Bay, New Zealand
Health New Zealand, Te Whatu Ora Waitemata, North Shore Hospital
Auckland, New Zealand
Auckland City Hospital
Auckland, New Zealand
Aotearoa Clinical Trials Trust, Middlemore Hospital
Auckland, New Zealand
201 Great King Street, Central Dunedin, Dunedin 9016, New Zealand
Dunedin, New Zealand
Private Bag 9742 Maunu Road, Horahora, Whangārei 0148, New Zealand
Whangarei, New Zealand
Hospital Clinico Universitario València (INCLIVA)
Valencia, Espana, Spain
National Nephrology Specialized Hospital
Colombo, Polonnaruwa, Sri Lanka
National Hospital of Sri Lanka
Colombo, Sri Lanka
Kandy National Hospital
Kandy, Sri Lanka
Kurunegala Teaching Hospital
Kurunegala, Sri Lanka
Sri Jayewardenepura General Hospital
Nugegoda, Sri Lanka
Peradeniya Teaching Hospital
Peradeniya, Sri Lanka
Colombo North Teaching Hospital
Ragama, Sri Lanka