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RECRUITING
NCT06059157
NA

Epileptogenic Network Visualisation With Advanced MRI

Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient. The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to: 1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification. Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.

Key Details

Gender

All

Age Range

3 Years - Any

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2023-10-25

Completion Date

2029-10

Last Updated

2024-03-18

Healthy Volunteers

No

Interventions

DEVICE

Advanced MRI

resting-state functional MRI, diffusion with advanced post-processing (microstructure analysis), myelin mapping

Locations (1)

Cliniques Universitaires St-Luc

Brussels, Belgium