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Epileptogenic Network Visualisation With Advanced MRI
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Summary
The goal of this clinical trial is to improve non-invasive identification of epileptogenic networks in drug-resistant epileptic patient. The investigators aim to compare epileptogenic network identification with stereo-EEG (used as glod standard) with the identification of the same network using advanced MRI (rs-fMRI, microstructural analysis of white matter, ...). The main goals are to: 1. Compare the accuracy of network identification. 2. Analyse the effect of the MRI sequences on candidates selection and target identification. Participants will already have been selected for stereoEEG and will undergo a supplementary MRI (about 1h) with the additional MRI sequences. Follow-up MRI are scheduled for patient undergoing a second, therapeutic epileptic surgery.
Key Details
Gender
All
Age Range
3 Years - Any
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2023-10-25
Completion Date
2029-10
Last Updated
2024-03-18
Healthy Volunteers
No
Conditions
Interventions
Advanced MRI
resting-state functional MRI, diffusion with advanced post-processing (microstructure analysis), myelin mapping
Locations (1)
Cliniques Universitaires St-Luc
Brussels, Belgium