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Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation
Sponsor: University of California, Davis
Summary
The goal of this clinical trial is to determine if pulse oximeters show an SaO2-SpO2 discrepancy that correlates with skin pigmentation such that pulse oximetry will overestimate oxygenation in newborns with darker skin. The main questions it aims to answer is if SaO2-SpO2 discrepancy varies with the degree of skin pigmentation among neonates, if gestational age has an influence on SaO2-SpO2 discrepancy, and if packed red blood cell (PRBC) transfusion has an influence on SaO2-SpO2 discrepancy in newborns with various degrees of light and dark skin. Researchers will compare SaO2 and SpO2 values in neonates of various skin pigmentation.
Key Details
Gender
All
Age Range
Any - 10 Days
Study Type
INTERVENTIONAL
Enrollment
163
Start Date
2022-04-01
Completion Date
2026-04
Last Updated
2026-02-20
Healthy Volunteers
Yes
Conditions
Interventions
Enrolled Participant
Participant will undergo at most 10 SpO2 measurements paired with at most 10 routine blood gas samples.
Locations (2)
UC Davis Health
Sacramento, California, United States
University of Mississippi Medical Center
Jackson, Mississippi, United States