Clinical Research Directory

Inclusion Criteria: 1. Age ≥18 years 2. Planned lower limb revascularization surgical procedure (on an elective or urgent basis): infrainguinal arterial bypass, femoral endarterectomy, patch angioplasty 3. Able to access a telephone for postoperative follow-up Exclusion Criteria: 1. Absolute contraindications to neuraxial anesthesia: impaired coagulation state (due to intrinsic, congenital or extrinsic (i.e., anticoagulant not held for guideline recommended period based on the American Society of Regional Anesthesia recommendations) factors), infection at the needle insertion point, increased intracranial pressure or intracranial mass, uncorrected hypovolemia or hypotension (systolic blood pressure \<90 mmHg), severe uncorrected aortic stenosis) 2. Traumatic arterial injuries as an indication for surgery 3. Multiple sclerosis or demyelinating central nervous system conditions 4. Known malignant hyperthermia or who require a malignant hyperthermia trigger-free anesthetic 5. Pregnancy 6. Prior enrollment in this study, or participating in another interventional trial that could interfere with interpretation of data for either study (may be acceptable if unrelated interventions/outcomes and study PIs mutually agree in writing to co-enrollment) 7. Determination by the surgeon, anesthesiologist, or other clinician, that the patient would not be suitable for randomization