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The Computational and Neural Mechanisms Linking Decision-making and Memory in Humans
Sponsor: Rutgers, The State University of New Jersey
Summary
Learning to make good decisions in the present, and accurately recalling events and information from the past, are critical aspects of human cognition that are often impaired in many psychiatric disorders. This project aims to identify the how the choices individuals make influence what, and how, people remember by combining disparate techniques in computational modeling and direct brain recordings in human subjects. The researcher developed a dual-task paradigm, probing how decisions in one task affect immediate recognition memory. To examine the neural mechanisms underlying model-free RL's influence on memory, the researcher will record local field potential (LFP) and single neuron activity in various brain regions as epilepsy patients perform the proposed task. The results of this project will identify specific neurocomputational mechanisms unifying decision-making and memory processes.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-10-31
Completion Date
2028-09-01
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Value-manipulation
During the decision-making task, different choices are assigned different values probabilistically.
Locations (1)
Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey, United States