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RECRUITING
NCT06072924
NA

K01 Impacts of Lingual Endurance Exercise

Sponsor: University of Cincinnati

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke. It also aims to explore how this exercise may affect brain structure and connectivity involved in swallowing. The main questions it aims to answer are: Primary Aim: Does lingual endurance exercise improve swallowing function compared to a sham therapy? Secondary Aim: Does lingual endurance exercise lead to changes in brain structure or neuroplasticity, as measured by MRI? Researchers will compare a group receiving tongue endurance exercises to a sham therapy group to see whether the treatment improves tongue function, swallowing. Participants will: * Complete a baseline swallowing assessment and MRI * Be randomly assigned to either the lingual exercise or sham therapy group * Complete 8 weeks of home-based tongue exercise therapy * Return for follow-up swallowing assessments * A subgroup of participants will complete a pre-treatment and post-treatment MRI.

Official title: Impact of Lingual Endurance Exercise on Rehabilitation of Swallowing Impairments After Ischemic Stroke

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2023-09-01

Completion Date

2028-08-31

Last Updated

2025-12-18

Healthy Volunteers

No

Interventions

BEHAVIORAL

Isotonic Endurance Exercise

Pressing tongue against a pressure sensor at the set number of repetitions per session (individualized per participant) 3 times per day

BEHAVIORAL

Sham Exercise

Pressing tongue against pressure sensor at a low threshold (1-15kPa) 30x/day

Locations (1)

University of Cincinnati

Cincinnati, Ohio, United States