Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
Sponsor: Seattle Children's Hospital
Summary
This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
Key Details
Gender
All
Age Range
0 Days - 55 Years
Study Type
INTERVENTIONAL
Enrollment
116
Start Date
2023-06-09
Completion Date
2027-06-09
Last Updated
2026-04-30
Healthy Volunteers
No
Conditions
Interventions
Standard of Care
Standard of care arm: Mothers will consent to providing DHM (if qualifies per hospital policy) or formula if MOM is not available. Infants are only eligible to receive donor milk only if 1) MOM is not available 2) if infant initiates feeds before day 3 of age. The donor milk feed would be stopped on day 5 of age.
Exclusive Human Milk
Mothers will consent to providing DHM if MOM is not available. If the infant reaches 100 ml/kg/day of feeds (one feed advancement prior to full feeds) and MOM remains unavailable, they will transition to formula in preparation for discharge. Infants cannot be discharged on donor milk.
Locations (1)
Seattle Children's Hospital
Seattle, Washington, United States