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Addressing Genomic Disparities in Cancer Survivors
Sponsor: Rutgers, The State University of New Jersey
Summary
The goal of this observational study is to increase genetic education and genetic testing for hereditary cancer risk among Black cancer survivors. The study will: 1. Test the effectiveness of a chatbot intervention (also called relational agent, or RA) vs. enhanced usual care (EUC) on engagement in genetic education and requests for genetic testing. 2. Evaluate the impact of the chatbot vs. EUC on the process that participants use to make decisions and evaluate effects on well-being (also called psychosocial outcomes). 3. Explore the ways (methods) that influence how participants experience the intervention. 4. Explore the feasibility of incorporating a Family Sharing Portal (FSP) for participants who receive a positive test result, to facilitate family communication of these test results and genetic testing of first-degree biological relatives after they have received genetic education by the RA. The main questions this study aims to answer are which group - the chatbot (RA) group or the EUC group - is more likely to request genetic testing and which group is more likely to get (engage with) genetic education. Participants will be randomly assigned to either the chatbot (RA) group or EUC group. This means each participant has an equal chance of being placed in either group, just like flipping a coin. Each group will receive genetic education and have an opportunity to request genetic testing. Researchers will compare the chatbot (RA) group and the EUC group to see which may request more GT (genetic testing) and which group engages more with genetic education.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
428
Start Date
2024-07-31
Completion Date
2027-08-31
Last Updated
2025-10-28
Healthy Volunteers
Yes
Conditions
Interventions
Relational agent (RA) / Chatbot
Consists of clinical letter and engagement with genetic education and uptake of genetic testing for hereditary cancer risk among Black cancer survivors.
Enhanced Usual Care (EUC)
Consists of clinical letter and recommendation for genetic testing for hereditary cancer risk among Black cancer survivors.
Locations (2)
Georgetown Lombardi Comprehensive Cancer Center
Washington D.C., District of Columbia, United States
Rutgers Cancer Institute
New Brunswick, New Jersey, United States