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RECRUITING
NCT06082492
NA

The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients

Sponsor: Radboud University Medical Center

View on ClinicalTrials.gov

Summary

The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F-Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography (18F FDG PET/CT) versus follow-up with conventional CT surveillance. Participants will receive usual care until 3 years of follow-up (control group) with additional whole-body 18F FDG PET/CT scans during follow-up visits at 6 months, 12 months, 18 months, 24 months, and 36 months of follow-up in the intervention group. Other tasks include: * filling in quality of life (QOL) questionnaires at every time point; * participating in an interview evaluating the addition of the 18F FDG PET/CT scans (optional); * collecting blood at the follow-up time points for our secondary endpoint (optional). Researchers will compare the usual care control group with the intervention group to see if the additional 18F FDG PET/CT scans are (cost-)effective.

Official title: The Beneficial Value of 18F FDG PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients: the NVALT31-PET Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

690

Start Date

2024-03-19

Completion Date

2029-06

Last Updated

2025-02-05

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

18F FDG PET/CT

Additional 18F FDG PET/CT scans during follow-up visits at 6, 12, 18, 24 and 36 months of follow-up.

DIAGNOSTIC_TEST

CT scan

CT of the thoracic region during follow-up visits at 6, 12, 18, 24 and 36 months of follow-up.

Locations (27)

Tergooi MC

Hilversum, Utrecht, Netherlands

Amsterdam UMC

Amsterdam, Netherlands

Antoni van Leeuwenhoek/Nederlands Kanker Instituut

Amsterdam, Netherlands

OLVG

Amsterdam, Netherlands

Gelre Ziekenhuizen

Apeldoorn & Zutphen, Netherlands

Amphia Ziekenhuis

Breda, Netherlands

Deventer Ziekenhuis

Deventer, Netherlands

Ziekenhuis Gelderse Vallei

Ede, Netherlands

Máxima Medisch Centrum

Eindhoven & Veldhoven, Netherlands

Treant

Emmen, Netherlands

Medisch Spectrum Twente

Enschede, Netherlands

Groene Hart Ziekenhuis

Gouda, Netherlands

Martini Ziekenhuis

Groningen, Netherlands

Tjongerschans ziekenhuis

Heerenveen, Netherlands

Dijklander Ziekenhuis

Hoorn, Netherlands

Canisius Wilhelmina Ziekenhuis

Nijmegen, Netherlands

Radboudumc

Nijmegen, Netherlands

Bravis Ziekenhuis

Roosendaal, Netherlands

Maasstad ZIekenhuis

Rotterdam, Netherlands

Franciscus Gasthuis & Vlietland

Schiedam, Netherlands

Haaglanden Medisch Centrum

The Hague, Netherlands

HagaZiekenhuis

The Hague, Netherlands

Elisabeth-TweeSteden Ziekenhuis

Tilburg, Netherlands

Diakonessenhuis

Utrecht, Netherlands

UMC Utrecht

Utrecht, Netherlands

St. Antonius Ziekenhuis

Utrecht & Nieuwegein, Netherlands

Streekziekenhuis Koningin Beatrix

Winterswijk, Netherlands