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RECRUITING
NCT06083064
NA

Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis

Sponsor: Helsinki University Central Hospital

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare protocol based selective imaging to routine imaging in adult patients with suspected appendicitis. The main question\[s\] it aims to answer are: * Does protocol based selective imaging using clinical scoring affect clinical outcome? * Does protocol based selective observation combined with score based selective imaging affect clinical outcome? Participants will be randomized into three groups: * Selective imaging based on Adult Appendicitis Score * Selective observation based on Appendicitis Severity Score combined with selective imaging based on Adult Appendicitis Score * Routine imaging using ultrasound and/or computed tomography Researchers will compare selective imaging groups separately with routine imaging to see if number of negative appendectomies or number of complicated appendicitis is not significantly increased.

Official title: Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis (PROSECCO)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

900

Start Date

2023-11-15

Completion Date

2028-12-31

Last Updated

2025-03-12

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

Abdominal imaging

Abdominal ultrasound and/or abdominal CT

OTHER

Score based selective abdominal imaging

Abdominal imaging is done selectively based on Adult Appendicitis Score

OTHER

Score based selective observation combined with selective abdominal imaging

Observation based on Appendicitis Severity Score combined Adult Appendicitis Score based selective abdominal imaging

Locations (3)

HUS, Jorvi Hospital

Espoo, Finland

HUS, Meilahti Hospital

Helsinki, Finland

HUS, Hyvinkää Hospital

Hyvinkää, Finland