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Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis
Sponsor: Helsinki University Central Hospital
Summary
The goal of this clinical trial is to compare protocol based selective imaging to routine imaging in adult patients with suspected appendicitis. The main question\[s\] it aims to answer are: * Does protocol based selective imaging using clinical scoring affect clinical outcome? * Does protocol based selective observation combined with score based selective imaging affect clinical outcome? Participants will be randomized into three groups: * Selective imaging based on Adult Appendicitis Score * Selective observation based on Appendicitis Severity Score combined with selective imaging based on Adult Appendicitis Score * Routine imaging using ultrasound and/or computed tomography Researchers will compare selective imaging groups separately with routine imaging to see if number of negative appendectomies or number of complicated appendicitis is not significantly increased.
Official title: Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis (PROSECCO)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
900
Start Date
2023-11-15
Completion Date
2028-12-31
Last Updated
2025-03-12
Healthy Volunteers
No
Conditions
Interventions
Abdominal imaging
Abdominal ultrasound and/or abdominal CT
Score based selective abdominal imaging
Abdominal imaging is done selectively based on Adult Appendicitis Score
Score based selective observation combined with selective abdominal imaging
Observation based on Appendicitis Severity Score combined Adult Appendicitis Score based selective abdominal imaging
Locations (3)
HUS, Jorvi Hospital
Espoo, Finland
HUS, Meilahti Hospital
Helsinki, Finland
HUS, Hyvinkää Hospital
Hyvinkää, Finland