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Translation and Validation of the COMM and ASI-SR
Sponsor: Uppsala University
Summary
The goal of this observational study is to translate the COMM (Current opinion misuse measure) form and validate it using the ASI-SR (Addiction severity score-self report)in a Swedish population of pain patients treated with opioids. The secondary aim is to investigate acceptability of the instrument in a Swedish population of pain patients with long-term opioid treatment (LOT). The tertiary aim is to investigate the prevalence of alcohol and illicit substance use in a Swedish population of pain patients with LOT.
Official title: Translation and Validation of the COMM and ASI-SR - Instruments for Assessing Substance Use Disorder Development in a Swedish Population of Patients With Long-term Pain Treated With Opioids
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2023-12-01
Completion Date
2026-12-31
Last Updated
2024-05-10
Healthy Volunteers
No
Interventions
Current Opioid Misuse Measure (COMM)-SWE
Patients in test group should fulfill the the COMM and the battery of validation forms as well as leave the oral fluid for illicit drugs test and whole blod for phosphatidylethanol test.
Oral fluid drug test
Oral fluid sampling to detect drugs. Analysis with LC-HRMS
PETh
Alcohol use detection
ASI-SR
Cross-validation form
AUDIT
Cross-validation form
DUDIT
Cross-validation form
Brief Pain Inventory - BPI
Cross-validation form
Patient Global Impression of Change PGIC
Cross-validation form
GAD-7
Cross-validation form
Patient Health questionnaire (PHQ9)
Cross-validation form
DBS - cannabis test
cross-validation form
Sample of Blood for later DNA and immunological analysis in future studies
sample collection for future studies
Locations (1)
Multidisciplinary Pain Center
Uppsala, Uppland, Sweden