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Comparison Between Intra-articular Infiltrations of PRP, MFAT, and PRP-MFAT in the Treatment of Symptomatic Knee Osteoarthritis.
Sponsor: Assistance Publique Hopitaux De Marseille
Summary
This research protocol evaluate the efficacity of intra-articular injections of autologous microfat associated with a preparation of autologous PRP, in symptomatic, resistant to first-line medical treatment, degenerative or post-traumatic cartilage lesions of the knee. The primary objective of this study is to show the superiority of intra-articular injection of autologous microfat combined with autologous PRP preparation compared to injection of microfat or PRP used alone, on the KOOS score at 6 months.
Official title: Randomized Control Trial Comparison Between Intra-articular Infiltrations of PRP, MFAT, and PRP-MFAT in the Treatment of Symptomatic Knee Osteoarthritis.
Key Details
Gender
All
Age Range
20 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2024-02-02
Completion Date
2028-03-01
Last Updated
2023-10-27
Healthy Volunteers
No
Conditions
Interventions
Intra-articular injection of autologous microfat
A preparation of autologous microfat (5mL) will be injected intra-articularly.
Intra-articular injection of autologous platelet-rich plasma
A preparation of autologous platelet-rich plasma (5mL) will be injected intra-articularly.
Intra-articular injection of autologous microfat and platelet-rich plasma
A preparation of autologous platelet-rich plasma (5mL) and autologous microfat (5mL) will be injected intra-articularly.