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Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles
Sponsor: University of Connecticut
Summary
The goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell profiles in younger vs. older men and women. The study will address the following objectives: * Objective 1: Determine if daily consumption of egg fractions differentially alter HDL profiles across age groups. * Objective 2: Determine if daily consumption of egg fractions differentially alter immune cell profiles across age groups. Participants will be asked to consume egg whites, egg yolks, and whole eggs on a daily basis for 4-weeks each, and avoid eating eggs for a total of 8 weeks at different points in the study. Participants will additionally be provided guidance on following a generally healthy diet, and will be asked to complete surveys about dietary intake and physical activity, as well as provide blood samples throughout the course of the study. Researchers will compare whether daily consumption of egg whites, egg yolks, and whole eggs differentially alter markers of HDL function and T cell profiles in younger vs. older adults.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2024-01-23
Completion Date
2026-06
Last Updated
2025-08-05
Healthy Volunteers
Yes
Conditions
Interventions
Whole eggs
3 large whole eggs per day for 4 weeks
Egg yolks
3 large egg equivalent of egg yolks per day for 4 weeks
Egg whites
3 large egg equivalent of egg whites per day for 4 weeks
Locations (1)
University of Connecticut
Storrs, Connecticut, United States