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RECRUITING
NCT06088589
NA

Speech-in-noise Perception in Autism and Fragile X

Sponsor: Children's Hospital Medical Center, Cincinnati

View on ClinicalTrials.gov

Summary

The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact. The investigators are studying brain activation during speech-in-noise in autism and controls as well as individuals with Fragile X Syndrome. The main question\[s\] it aims to answer are: 1) How does the brain's response to background noise affect a person's ability to understand speech? 2) Can visual cues improve hearing in background noise? Participants will complete the following: * hearing tests * cognitive and behavioral measures * questionnaires about their symptoms * both passive and active hearing tasks while brain activity is recorded with a neuroimaging cap Results will be compared between individuals with autism with and without Fragile X Syndrome as well as individuals without autism.

Official title: Cortical Mechanisms of Speech in Noise Perception in Autism and Fragile X Syndrome

Key Details

Gender

All

Age Range

15 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2023-11-10

Completion Date

2026-04-30

Last Updated

2026-03-19

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Mismatch negativity

Event related potentials are compared between frequent and infrequent speech sounds (i.e., "ba" vs "da").

Locations (1)

Cincinnati Children'S Hospital

Cincinnati, Ohio, United States