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Speech-in-noise Perception in Autism and Fragile X
Sponsor: Children's Hospital Medical Center, Cincinnati
Summary
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact. The investigators are studying brain activation during speech-in-noise in autism and controls as well as individuals with Fragile X Syndrome. The main question\[s\] it aims to answer are: 1) How does the brain's response to background noise affect a person's ability to understand speech? 2) Can visual cues improve hearing in background noise? Participants will complete the following: * hearing tests * cognitive and behavioral measures * questionnaires about their symptoms * both passive and active hearing tasks while brain activity is recorded with a neuroimaging cap Results will be compared between individuals with autism with and without Fragile X Syndrome as well as individuals without autism.
Official title: Cortical Mechanisms of Speech in Noise Perception in Autism and Fragile X Syndrome
Key Details
Gender
All
Age Range
15 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2023-11-10
Completion Date
2026-04-30
Last Updated
2026-03-19
Healthy Volunteers
Yes
Interventions
Mismatch negativity
Event related potentials are compared between frequent and infrequent speech sounds (i.e., "ba" vs "da").
Locations (1)
Cincinnati Children'S Hospital
Cincinnati, Ohio, United States