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Micro-expressions in Patients With Prolonged Disorders of Consciousness
Sponsor: First Affiliated Hospital of Zhejiang University
Summary
The goal of this observational study is to learn about the microexpressions in patients with prolonged disorders of consciousness. The main questions it aims to answer are: * Inducing micro-expression changes in patients with prolonged disorders of consciousness through various emotional stimuli, and further to achieve precise classification of their levels of consciousness. * Detecting micro-expressions in patients with prolonged disorders of consciousness to assist clinical diagnosis of levels of consciousness, e.g., complement the disgnosis of clinical scales such as CRS-r scale. * By monitoring micro-expression changes in patients with prolonged disorders of consciousness, researchers can explore their residual brain function, thereby advancing research into relevant neural mechanisms. Participants will be subjected to consciousness assessment by CRS-r scale, and their micro-expression changes in response to various emotional stimuli will be captured, along with the collection of EEG and MRI data. Follow-up evaluations will be conducted using the CRS-R scale and GOS scale, with a follow-up period of 6 months.
Official title: Study of Micro-expressions in Patients With Prolonged Disorders of Consciousness
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-09-27
Completion Date
2026-12
Last Updated
2026-01-14
Healthy Volunteers
Yes
Conditions
Interventions
Facial expression; Electroencephalogram; MRI
Recording facial expressions of participants, EEG recordings, and MRI scans.
Locations (1)
First Affiliated Hospital,Zhejiang University
Hangzhou, Zhejiang, China