Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06088628

Micro-expressions in Patients With Prolonged Disorders of Consciousness

Sponsor: First Affiliated Hospital of Zhejiang University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about the microexpressions in patients with prolonged disorders of consciousness. The main questions it aims to answer are: * Inducing micro-expression changes in patients with prolonged disorders of consciousness through various emotional stimuli, and further to achieve precise classification of their levels of consciousness. * Detecting micro-expressions in patients with prolonged disorders of consciousness to assist clinical diagnosis of levels of consciousness, e.g., complement the disgnosis of clinical scales such as CRS-r scale. * By monitoring micro-expression changes in patients with prolonged disorders of consciousness, researchers can explore their residual brain function, thereby advancing research into relevant neural mechanisms. Participants will be subjected to consciousness assessment by CRS-r scale, and their micro-expression changes in response to various emotional stimuli will be captured, along with the collection of EEG and MRI data. Follow-up evaluations will be conducted using the CRS-R scale and GOS scale, with a follow-up period of 6 months.

Official title: Study of Micro-expressions in Patients With Prolonged Disorders of Consciousness

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2022-09-27

Completion Date

2026-12

Last Updated

2026-01-14

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Facial expression; Electroencephalogram; MRI

Recording facial expressions of participants, EEG recordings, and MRI scans.

Locations (1)

First Affiliated Hospital,Zhejiang University

Hangzhou, Zhejiang, China