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Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment
Sponsor: The University of Hong Kong
Summary
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive sequelae. Chronic intermittent hypoxia, sleep fragmentation of OSA, and insufficient sleep have been significantly associated with higher risks of neurocognitive impairment, including mild cognitive impairment (MCI) and Alzheimer's disease. Thus, sleep and circadian function might be modifiable neurocognitive impairment factors. The significance of the study is to understand the relationships of MCI with sleep apnea and sleep-related symptoms, which helps pave the groundwork for further research.
Official title: Exploring the Association of Sleep Apnea With Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2023-03-07
Completion Date
2027-03-31
Last Updated
2025-04-02
Healthy Volunteers
Yes
Interventions
Home Sleep Apnea test (HSAT)
Patient will received HSAT at baseline
Locations (1)
Queen Mary Hospital
Hong Kong, Hong Kong