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SASL Swiss Cirrhosis Cohort
Sponsor: University Hospital, Basel, Switzerland
Summary
This is a national prospective long-term multicentre observational cohort study following patients with cirrhosis in order to systematically and longitudinally record epidemiological, clinical, histological, psychosocial and patient-reported data and biobank biological material from patients with cirrhosis. The central element of all scientific operation and productivity in the Swiss Cirrhosis Cohort Study (SSCiCoS) is the so-called "nested project" (NP). Based on the evolving large pool of data and biological samples, SSCiCoS investigators use the data pool in order to investigate specific hypotheses and questions.
Official title: SASL Swiss Cirrhosis Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
3000
Start Date
2024-06-04
Completion Date
2033-01
Last Updated
2025-07-08
Healthy Volunteers
Yes
Conditions
Interventions
Data collection
Clinical assessment and blood sampling at day of inclusion and in 6- monthly intervals for stable cirrhotic patients; at day of inclusion and on days 3, 7, 14 and 28 for acute decompensation or acute-on-chronic liver failure patients; assessment of clinical, psychosocial/behavioural and patient-reported data in parallel with blood sampling; * Biobanking of PBMCs and serum/plasma samples * Biobanking of other biological material if sampled for clinical reasons (liver biopsies, ascites, urine, gut mucosa, lymph nodes)
Locations (10)
Gastroenterology and Hepatology, Cantonal Hospital Ticino
Lugano, Canton Ticino, Switzerland
University Centre for Gastrointestinal and Liver Diseases, University Hospital Basel, Switzerland
Basel, Switzerland
Department of Visceral Surgery and Medicine, University Hospital of Berne
Bern, Switzerland
Gastroenterology and Hepatology, University Hospital Geneva
Geneva, Switzerland
Gastroenterology and Hepatology, Lausanne University Hospital
Lausanne, Switzerland
Ticino Liver Centre
Lugano, Switzerland
Gastroenterology and Hepatology, Cantonal Hospital St. Gallen
Sankt Gallen, Switzerland
Arud Centre for addiction medicine Zurich
Zurich, Switzerland
Digestive Diseases Insti- tute GastroZentrum, Hirslanden Clinic Zurich
Zurich, Switzerland
Gastroenterology and Hepatology, University Hospital Zurich
Zurich, Switzerland