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ACTIVE NOT RECRUITING
NCT06094153
NA

Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Sponsor: Kyowa Hakko Bio Co., Ltd.

View on ClinicalTrials.gov

Summary

Human Milk Oligosaccharides (HMOs) are the third most abundant class of nutrients in human milk. Studies investigating the effects of dietary HMOs in infants have shown various health and developmental benefits such as the development of the early gut microbiome (by favouring colonisation of beneficial Bifidobacterium, Lactobacillus, and Bacteroides), the development of the immune system, general infant growth, protection against infectious diseases and allergies, and stimulation of cognitive development. Only a limited number of studies have been conducted in adults, showing intake of HMOs stimulates the growth of gut Bifidobacterium in healthy adults.

Official title: Randomized Controlled Trial on Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function

Key Details

Gender

All

Age Range

40 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

108

Start Date

2023-10-04

Completion Date

2025-09

Last Updated

2025-02-05

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Placebo

Consume placebo (Maltodextrin) once daily before going to bed for 28 days

DIETARY_SUPPLEMENT

HMO 1

Consume HMO 1 (Dietary supplement) once daily before going to bed for 28 days

DIETARY_SUPPLEMENT

HMO 2

Consume HMO 2 (Dietary supplement) once daily before going to bed for 28 days

Locations (1)

Singapore Institute for Clinical Trials

Singapore, Singapore