Clinical Research Directory
Browse clinical research sites, groups, and studies.
Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function
Sponsor: Kyowa Hakko Bio Co., Ltd.
Summary
Human Milk Oligosaccharides (HMOs) are the third most abundant class of nutrients in human milk. Studies investigating the effects of dietary HMOs in infants have shown various health and developmental benefits such as the development of the early gut microbiome (by favouring colonisation of beneficial Bifidobacterium, Lactobacillus, and Bacteroides), the development of the immune system, general infant growth, protection against infectious diseases and allergies, and stimulation of cognitive development. Only a limited number of studies have been conducted in adults, showing intake of HMOs stimulates the growth of gut Bifidobacterium in healthy adults.
Official title: Randomized Controlled Trial on Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function
Key Details
Gender
All
Age Range
40 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
108
Start Date
2023-10-04
Completion Date
2025-09
Last Updated
2025-02-05
Healthy Volunteers
Yes
Conditions
Interventions
Placebo
Consume placebo (Maltodextrin) once daily before going to bed for 28 days
HMO 1
Consume HMO 1 (Dietary supplement) once daily before going to bed for 28 days
HMO 2
Consume HMO 2 (Dietary supplement) once daily before going to bed for 28 days
Locations (1)
Singapore Institute for Clinical Trials
Singapore, Singapore