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Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Sponsor: Rigshospitalet, Denmark
Summary
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes. However, there is limited evidence supporting its use in the acute setting. So far, no large-scale randomized trial has examined the performance of CCTA as an alternative to invasive coronary angiography (ICA) in individuals with non-ST-segment elevation myocardial infarction (NSTEACS). If CCTA were to replace ICA as a routine procedure for individuals with NSTEACS, it could reduce the risk of complications related to ICA, improve patient comfort, expedite decision-making, and reduce healthcare expenses and interhospital transfers.
Official title: Team-based Interventional Triage in Acute Coronary Syndrome Based on Non-Invasive Computed Tomography Coronary Angiography - a Randomized Trial
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
2300
Start Date
2023-10-01
Completion Date
2036-10-01
Last Updated
2025-02-19
Healthy Volunteers
No
Conditions
Interventions
CCTA
Participants will be examined with CCTA during admission.
Conventional ICA
Patients will be examined with conventional standard-of-care ICA.
Team-based interventional triage
The CCTA will be discussed at a coronary CT-team conference to establish the treatment strategy and provide guidance for any necessary interventional procedure.
Locations (6)
Herlev and Gentofte Hospital
Copenhagen, Hellerup, Denmark
Bispebjerg Hospital
Bispebjerg, Denmark
Rigshospitalet
Copenhagen, Denmark
Zealand University Hospital
Copenhagen, Denmark
North Zealand Hospital
Hillerød, Denmark
Hvidovre Hospital
Hvidovre, Denmark