Clinical Research Directory

inclusion criteria: * suffering from a hematological malignancy (Myelodysplasia, Leukemia of any type, Lymphoma, Myeloma) * patient affiliated to a social security insurance * Patient undergoing or scheduled chemotherapy (\< 3 months) and/or immunotherapy and/or targeted therapy. Exclusion criteria: * Life expectancy estimated at less than 3 months by the unit doctor; * Cognitive impairment (not allowing comprehension of the physical activity program and research project) defined by Mini-Mental State Examination (MMSE) \<20/30; * Patient included in a clinical trial that potentially interferes with the study objective (geriatric interventional study, early drug study, study modifying the patient's lifestyle habits).; * Acute health problem (fever, severe anemia, intense pain, etc.) limiting the possibility of involvement in the program; * Contraindication to physical activity; * Patient under legal protection (guardianship or curatorship or safeguard of justice); * Refusal of patient or primary caregiver to participate.