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GUIDING MULTI-MODAL THERAPIES AGAINST MINIMAL RESIDUAL DISEASE BY LIQUID BIOPSIES
Sponsor: Karolinska University Hospital
Summary
The overall objective of this study is to confirm that ctDNA detected after curative intended treatment for PDAC is a marker of residual disease and for risk-of-recurrence, and applicable in clinical practice. Primary objective To confirm that ctDNA analyses performed after PDAC treatment can identify patients with a high risk-of-recurrence. Specifically, we want to determine the association between disease-free survival (DFS) and ctDNA detection status after (1) curative-intended surgery and (2) adjuvant chemotherapy.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2024-05-02
Completion Date
2026-12-31
Last Updated
2024-04-24
Healthy Volunteers
Not specified
Conditions
Interventions
liquid biopsy
Taking blood samples (liquid biopsy) for multiple analysis in genomics, proteomics, and metabolomics
Locations (1)
Gastrocentrum, KarolinskaUniversity Hospital
Stockholm, Sweden