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NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia
Sponsor: Attikon Hospital
Summary
The aim of this study is to investigate the hypothesis that the intraoperative use of the nociception level index NOL can reduce opioid consumption in adult patients undergoing elective laparoscopic surgeries under general anesthesia, as well as to explore its effect on post-operative pain and patient recovery.
Official title: Ιntraoperative Administration of Opioids Guided by the Nociception Level Index NOL in Elective Laparoscopic Surgeries Under General Anesthesia: Effect on Opioid Consumption, Post-operative Pain and Patient Recovery
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2023-04-20
Completion Date
2026-09-20
Last Updated
2025-04-03
Healthy Volunteers
No
Conditions
Interventions
Nociception level index (NOL™)
If a NOL value \>25 persists for \>1 minute a bolus of iv fentanyl 0.5mcg/kg will be given and reassessment of the NOL value will continue every 5 minutes. If NOL index value: 10-25 is not reached within 10 minutes, fentanyl 0.5mcg/kg iv is re-administered.
Fentanyl
Bolus doses of iv fentanyl 0.5 mcg/kg will be administered based on the judgment of the anesthesiologist in charge.
Locations (1)
2nd Department of Anesthesiology, Attikon University Hospital
Athens, Attica, Greece