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Indicator Amino Acid Oxidation in ICU Patients
Sponsor: Maastricht University Medical Center
Summary
This study will use the indicator amino acid oxidation technique (IAAO) to determine protein oxidation of ICU patients at two protein intakes: 1.3 g/kg/d versus 2.0 g/kg/d.
Official title: The Effect of Standard or Higher Protein Feeding on Indicator Amino Acid Oxidation in ICU Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
8
Start Date
2023-10-30
Completion Date
2025-12
Last Updated
2024-11-29
Healthy Volunteers
No
Conditions
Interventions
Standard protein enteral nutrition with enteral tracer
Enteral nutrition with standard (1.3 g/kg/d) protein provision, given via a nasogastric tube. An oral L-\[1-13C\]-phenylalanine tracer is given as co-intervention. Use of an enterally given tracer is necessary to determine indicator amino acid oxidation.
High protein enteral nutrition with enteral tracer
Enteral nutrition with high (2.0 g/kg/d) protein provision, given via a nasogastric tube. An oral L-\[1-13C\]-phenylalanine tracer is given as co-intervention. Use of an enterally given tracer is necessary to determine indicator amino acid oxidation.
Locations (1)
Maastricht University Medical Center+
Maastricht, Limburg, Netherlands