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RECRUITING
NCT06107933

Developmental Impacts of Microplastics Exposure in Early Life

Sponsor: Johns Hopkins Bloomberg School of Public Health

View on ClinicalTrials.gov

Summary

The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothers and infants in mother-infant dyads 1 or 3 months postpartum living in Baltimore, Maryland. The main questions it aims to answer are: * What MNPs are present in breastmilk and maternal blood samples and in their infants stool sample? * Are there associations between amount of maternal MNPs in breast milk and mass of MNP particles in infant stool? * Which environmental and lifestyle factors are most predictive of maternal MNP burden? * Is infant exposure to MNPs associated with birth weight and postnatal growth trajectories? Participants will: * Complete several questionnaires assessing medical histories, lifestyle factors, environmental exposures, eating behaviors, etc. * Provide biological specimens including: maternal blood, stool, and breastmilk; infant stool * Clinical visit to have anthropometric measures documented including maternal height and weight, infant weight, length, and skin-fold thickness

Official title: Developmental Impacts of MicroPLastics Exposure in Early Life

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2023-10-01

Completion Date

2027-01-01

Last Updated

2025-06-10

Healthy Volunteers

Yes

Interventions

OTHER

Observational only

Exposure to micro and nano plastics

Locations (1)

East Baltimore Pediatric Inpatient and Outpatient Clinical Research Unit

Baltimore, Maryland, United States