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Cerebellar Involvement in Cognitive Sequencing
Sponsor: Johns Hopkins University
Summary
Although there is increasing recognition that the cerebellum is involved in cognition as well as motor function, the manner in which the cerebellum contributes to cognition is uncertain. One theory that might account for both motor and cognitive contributions of the cerebellum is that the cerebellum is involved in sequencing of relevant events or stimuli. Previous experiments have suggested that disruption of the cerebellum impairs the prediction of the next event in a sequence. The present experiment will examine the impact of cerebellar stimulation on brain activation during the performance of both sequence-demanding and non-sequence-demanding tasks.
Official title: Investigation of Cerebellar Involvement in Cognitive Sequencing
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-03-01
Completion Date
2027-07-31
Last Updated
2026-01-12
Healthy Volunteers
Yes
Interventions
TMS during sequence-demanding task
TMS is administered during the execution of sequence-demanding task. Transcranial magnetic stimulation (TMS) is a safe and non-invasive technique for transiently modulating brain activity
No TMS during sequence-demanding task
TMS is not administered during the execution of sequence-demanding task.
TMS during non-sequence-demanding task
TMS is administered during the execution of non-sequence-demanding task. Transcranial magnetic stimulation (TMS) is a safe and non-invasive technique for transiently modulating brain activity
No TMS during non-sequence-demanding task
TMS is not administered during the execution of non-sequence-demanding task
Locations (1)
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States