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The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery
Sponsor: Taichung Veterans General Hospital
Summary
The goal of this clinical trial is to the dose effect of tranexamic acid and the level of ACT on bleeding in adult cardiac surgery. The main questions it aims to answer are: 1. Does higher dose of tranexamic acid reduce the amount of bleeding and blood transfusion? 2. Does lower ACT level during cardiac surgery reduce the amount of bleeding and blood transfusion? Participants will divided into four groups which have different tranexamic acid dose and ACT level during cardiac surgery to see if there is any different in the amount of bleeding and blood transfusion.
Official title: The Dose Effect of Activated Clotting Time and Tranexamic Acid on Bleeding in Adult Cardiac Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-02-08
Completion Date
2026-12-31
Last Updated
2024-02-21
Healthy Volunteers
No
Interventions
Tranexamic acid
tranexamic acid will be used in two different doses (50mg/kg vs 20mg/kg). the tranexamic acid pump will start from the begin of anesthesia until all dose is administrated.
Locations (2)
Taichung Veterans General Hospital
Taichung, Taiwan
Taichung Veterans General hospital
Taichung, Taiwan