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RECRUITING
NCT06110143
NA

Oral Health and Adverse Pregnancy Complications

Sponsor: University Hospital Bispebjerg and Frederiksberg

View on ClinicalTrials.gov

Summary

Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of the offspring. Despite this, studies indicate that 40% of Danish women in childbearing age do not visit a dentist regularly. The PROBE controlled intervention study will investigate the beneficial effect of treatment of periodontal disease during pregnancy on fetal growth, preterm delivery and birth weight.

Official title: The Prevention of Adverse Pregnancy Outcomes by Periodontal Treatment (PROBE) Intervention Study

Key Details

Gender

FEMALE

Age Range

16 Years - 48 Years

Study Type

INTERVENTIONAL

Enrollment

600

Start Date

2021-11-13

Completion Date

2026-05

Last Updated

2025-03-30

Healthy Volunteers

Yes

Interventions

OTHER

Periodontal treatment

Periodontal treatment

Locations (3)

Holbaek Hospital

Holbæk, Holbaek, Denmark

Holbæk Hospital

Holbæk, Holbaek, Denmark

Nykøbing Falster Hospital

Nykøbing Falster, Nykøbing Falster, Denmark