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Oral Health and Adverse Pregnancy Complications
Sponsor: University Hospital Bispebjerg and Frederiksberg
Summary
Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of the offspring. Despite this, studies indicate that 40% of Danish women in childbearing age do not visit a dentist regularly. The PROBE controlled intervention study will investigate the beneficial effect of treatment of periodontal disease during pregnancy on fetal growth, preterm delivery and birth weight.
Official title: The Prevention of Adverse Pregnancy Outcomes by Periodontal Treatment (PROBE) Intervention Study
Key Details
Gender
FEMALE
Age Range
16 Years - 48 Years
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2021-11-13
Completion Date
2026-05
Last Updated
2025-03-30
Healthy Volunteers
Yes
Conditions
Interventions
Periodontal treatment
Periodontal treatment
Locations (3)
Holbaek Hospital
Holbæk, Holbaek, Denmark
Holbæk Hospital
Holbæk, Holbaek, Denmark
Nykøbing Falster Hospital
Nykøbing Falster, Nykøbing Falster, Denmark