Clinical Research Directory

Inclusion Criteria: 1. Willing and able to provide informed consent; 2. Subject meets the minimal safety criteria for single balloon enteroscopy: ASA Class I, II, or III;11 3. ≥ 18 years of age to ≤ 90 years of age; 4. Video capsule endoscopy identified lesions in the middle third of the small bowel; 5. Willing and able to comply with all study procedures and follow-up. Exclusion Criteria: 1. History of gastric bypass or related procedures; 2. History of foregut and/or midgut surgery; 3. Pathology identified by video capsule is in the proximal 1/3 of the bowel; 4. Pathology identified by video capsule is in the distal 1/3 of the bowel; 5. Anticoagulant and antiplatelet therapy that cannot be stopped for the enteroscopy; 6. Capsule endoscopy did not show clear visualization of pathology in the middle small bowel; 7. Inability to tolerate the investigator's method of sedation that is the standard of care; 8. Any previous small bowel surgery, or anastomosis, that caused extensive adhesions and/or altered anatomy; 9. Allergy to any medications or product used in the endoscopic procedure where the severe allergic reaction cannot be prevented with pre-medication; 10. Pregnancy; 11. Life expectancy \< six (6) months.