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Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)
Sponsor: NYU Langone Health
Summary
The purpose of this trial is to test the efficacy of a collaborative care intervention to address opioid- and/or stimulant-involved polysubstance use in adult primary care patients with moderate to severe substance use disorders (SUD). The primary aims are to reduce days of opioid use (illicit or nonmedical opioid use), days of illicit stimulant use (cocaine, methamphetamine), and days of heavy alcohol use.
Official title: NIDA CTN Protocol 0139: Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
350
Start Date
2025-01-31
Completion Date
2027-02
Last Updated
2026-02-06
Healthy Volunteers
No
Conditions
Interventions
Education and support for primary care providers (PCPS)
All PCPs in the EUC and Co-Care arms receive brief education on SUD treatment, including medications for OUD and AUD and contingency management for StUD, and recognizing and counteracting stigma while caring for patients with SUD.
Nurse Care Manager (NCM) visits
A full-time clinic-embedded nurse care manager who works with patients and their PCPs to facilitate and support patient engagement in evidence-based treatment for polysubstance use and management of associated health conditions
Addiction specialist consultant
An addiction specialist consultant who supports the nurse care manager and PCP in formulating and adjusting treatment plans
Health coaching sessions
Health coaches who use motivational interviewing and cognitive behavioral therapy to motivate and support patients in behavior change to reduce polysubstance use-related harms. Patients may receive up to 12 health coaching sessions in total. The sessions will occur via phone and/or HIPAA compliant video chat software.
Patient educational materials
Patient participants receive an educational pamphlet addressing overdose prevention, information about accessing naloxone, and local SUD treatment options.
Locations (8)
Harbor-UCLA Medical Center
Torrance, California, United States
NYU Langone Health
New York, New York, United States
The Institute for Family Health
New York, New York, United States
Winding Waters Medical Clinic
Enterprise, Oregon, United States
Union Community Care
Lancaster, Pennsylvania, United States
Harris Health
Houston, Texas, United States
Sea Mar Community Health Centers
Bellingham, Washington, United States
Wisconsin Research & Education Network
Madison, Wisconsin, United States