Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06116266
NA

Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)

Sponsor: NYU Langone Health

View on ClinicalTrials.gov

Summary

The purpose of this trial is to test the efficacy of a collaborative care intervention to address opioid- and/or stimulant-involved polysubstance use in adult primary care patients with moderate to severe substance use disorders (SUD). The primary aims are to reduce days of opioid use (illicit or nonmedical opioid use), days of illicit stimulant use (cocaine, methamphetamine), and days of heavy alcohol use.

Official title: NIDA CTN Protocol 0139: Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

350

Start Date

2025-01-31

Completion Date

2027-02

Last Updated

2026-02-06

Healthy Volunteers

No

Conditions

Interventions

OTHER

Education and support for primary care providers (PCPS)

All PCPs in the EUC and Co-Care arms receive brief education on SUD treatment, including medications for OUD and AUD and contingency management for StUD, and recognizing and counteracting stigma while caring for patients with SUD.

OTHER

Nurse Care Manager (NCM) visits

A full-time clinic-embedded nurse care manager who works with patients and their PCPs to facilitate and support patient engagement in evidence-based treatment for polysubstance use and management of associated health conditions

OTHER

Addiction specialist consultant

An addiction specialist consultant who supports the nurse care manager and PCP in formulating and adjusting treatment plans

OTHER

Health coaching sessions

Health coaches who use motivational interviewing and cognitive behavioral therapy to motivate and support patients in behavior change to reduce polysubstance use-related harms. Patients may receive up to 12 health coaching sessions in total. The sessions will occur via phone and/or HIPAA compliant video chat software.

OTHER

Patient educational materials

Patient participants receive an educational pamphlet addressing overdose prevention, information about accessing naloxone, and local SUD treatment options.

Locations (8)

Harbor-UCLA Medical Center

Torrance, California, United States

NYU Langone Health

New York, New York, United States

The Institute for Family Health

New York, New York, United States

Winding Waters Medical Clinic

Enterprise, Oregon, United States

Union Community Care

Lancaster, Pennsylvania, United States

Harris Health

Houston, Texas, United States

Sea Mar Community Health Centers

Bellingham, Washington, United States

Wisconsin Research & Education Network

Madison, Wisconsin, United States