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Systems Oncology Approach to Optimize Ovarian Cancer Treatment
Sponsor: University of Helsinki
Summary
The overall aim is to identify effective therapeutic strategies to ovarian cancer (OC) using serial tumor, ascites and blood samples, and carry out state-of-the-art sequencing approaches, functional assays and associated bioinformatics to understand mechanisms behind chemoresistance in OC and identify new treatment options for OC patients. In this observational trial, we will systematically collect, analyze and interpret functional, molecular and clinical data from real-world ovarian cancer patients.
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2022-01-01
Completion Date
2027-12-31
Last Updated
2023-11-07
Healthy Volunteers
No
Conditions
Interventions
Biomolecular profiling
Molecular and functional analysis of biospecimens, including tumor-normal Whole-exome sequencing, bulk and single-cell RNAsequencing, spatial proteomics, functional testing.
Locations (1)
Helsinki University and Helsinki University Hospital
Helsinki, Finland