Clinical Research Directory

Inclusion Criteria: 1. male or female patients aged 18 to 75 years; 2. patients with chronic kidney disease stage 5 who are to start PD; 3. eGFR ≥ 5 ml/min; 4. urine output ≥ 800 ml/d. Exclusion Criteria: 1. documented anaphylaxis with icodextrin or glucose-based dialysate; 2. concomitant severe chronic diseases such as malignancy, hepatitis, severe cardiac diseases, etc.; 3. ongoing severe infection; 4. planned or ongoing pregnancy or lactation; 5. currently enrolled in other clinical studies; 6. patients who have a life expectancy of \<12 months; 7. refusal to give a written consent.