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RECRUITING
NCT06120881
EARLY_PHASE1

Precision Dosing of Metformin in Youth With T2D

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).

Official title: Pilot Study of Precision Dosing of Metformin in Youth With Type 2 Diabetes (PRECISE_T2D)

Key Details

Gender

All

Age Range

10 Years - 21 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-04-25

Completion Date

2026-12-31

Last Updated

2025-12-23

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Metformin

Participants will receive either 2700mg of metformin/day (1350mg twice a day) or 2000mg of metformin/day (1000mg twice a day, standard of care). The study intervention will be blinded to the participants as they will receive the same number of pills (4 pills of the same size) regardless of whether they are in the intervention arm or control arm .

Locations (2)

UCSF Benioff Children's Hospital Oakland, Pediatric Diabetes Clinic

Oakland, California, United States

UCSF Benioff Children's Hospital San Francisco, Madison Clinic for Pediatric Diabetes

San Francisco, California, United States