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Efficacy and Safety of Carica Papaya in Dengue Fever: A Randomised Clinical Trial
Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Summary
This will be a placebo-controlled, multicenter-randomized prospective study of CPLE (Carica papaya leaf extract) tabs in dengue patients (WHO-Group A, B). The study will enroll 300 eligible dengue cases into two arms: one arm receiving CPLE 1000mg t.i.d for 5 days and the other group receiving a placebo. The main question to ask is whether CPLE reduces severe disease progression and increases platelet counts in dengue patients. The participant will be asked to take orally available CPLE capsules at a dose of 1000 mg (2 capsules, 500mg each) or identical placebo three times a day for 5 days
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2023-10-01
Completion Date
2023-12-27
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Interventions
Carica Papaya Leaf Extract
Active drug: CPLE 500mg 2 capsule t.i.d for 5 dayseive CPLE or placebo once daily for 5 days.
Placebo
Placebo: visually matched placebo 2 capsule t.i.d for 5 days
Locations (1)
Bangabandhu Sheikh Mujib Medical University
Dhaka, Bangladesh