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A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
Sponsor: Eli Lilly and Company
Summary
The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with Mazdutide compared with placebo and in adult participants with obesity or overweight. The study will last about 62 weeks.
Official title: A Phase 2, Parallel-Group, Double-Blind, 4-Arm Study to Investigate Weight Management With LY3305677 Compared With Placebo and in Adult Participants With Obesity or Overweight
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
179
Start Date
2023-11-17
Completion Date
2025-07-09
Last Updated
2026-04-21
Healthy Volunteers
No
Conditions
Interventions
Mazdutide
Administered subcutaneous (SC)
Placebo
Administered SC
Locations (29)
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa
Chandler, Arizona, United States
Headlands Research - Scottsdale
Scottsdale, Arizona, United States
The Institute for Liver Health II dba Arizona Liver Health-Tucson
Tucson, Arizona, United States
Velocity Clinical Research, Huntington Park
Huntington Park, California, United States
Peninsula Research Associates
Rolling Hills Estates, California, United States
Diablo Clinical Research, Inc.
Walnut Creek, California, United States
Northeast Research Institute (NERI)
Fleming Island, Florida, United States
Suncoast Clinical Research, Inc.
New Port Richey, Florida, United States
Charter Research - Winter Park
Orlando, Florida, United States
Charter Research - Lady Lake
The Villages, Florida, United States
Pacific Diabetes & Endocrine Center
Honolulu, Hawaii, United States
Great Lakes Clinical Trials - Andersonville
Chicago, Illinois, United States
Great Lakes Clinical Trials - Ravenswood
Chicago, Illinois, United States
Cotton O'Neil Diabetes & Endocrinology
Topeka, Kansas, United States
L-MARC Research Center
Louisville, Kentucky, United States
Knownwell
Needham, Massachusetts, United States
StudyMetrix Research
City of Saint Peters, Missouri, United States
Las Vegas Medical Research
Las Vegas, Nevada, United States
Dent Neurologic Institute
Amherst, New York, United States
North Suffolk Neurology
Port Jefferson Station, New York, United States
Lucas Research, Inc.
New Bern, North Carolina, United States
CTI Clinical Research Center
Cincinnati, Ohio, United States
Quality Medical Research
Nashville, Tennessee, United States
IMA Clinical Research Austin
Austin, Texas, United States
Velocity Clinical Research, Dallas
Dallas, Texas, United States
PlanIt Research, PLLC
Houston, Texas, United States
Tekton Research - Fredericksburg Road
San Antonio, Texas, United States
Spectrum Medical, Inc.
Danville, Virginia, United States
Central Washington Health Services Association d/b/a Confluence Health
Wenatchee, Washington, United States