Clinical Research Directory
Browse clinical research sites, groups, and studies.
BEP Targeting Strategies in Ethiopia
Sponsor: Harvard School of Public Health (HSPH)
Summary
The goal of this randomized effectiveness study is to evaluate the different targeting strategies for the delivery of balanced energy and protein (BEP) supplements among pregnant women in Addis Ababa, Ethiopia. The main goals of the study are to: 1) determine the effectiveness of two individual-based antenatal BEP targeting strategies for preventing adverse pregnancy outcomes; 2) compare the cost-effectiveness of the universal BEP provision with two individual-based targeting strategies for preventing adverse pregnancy outcomes; and 3) generate implementation evidence regarding the feasibility and acceptability of different antenatal BEP targeting strategies. Pregnant women will be enrolled during pregnancy, assigned to different strategies of BEP supplementation, and followed from pregnancy through six weeks postpartum to evaluate the impacts of different BEP targeting strategies on pregnancy, maternal, and child outcomes.
Official title: Targeting Strategies of Antenatal Balanced Energy and Protein Supplementation in Addis Ababa, Ethiopia
Key Details
Gender
FEMALE
Age Range
18 Years - 49 Years
Study Type
INTERVENTIONAL
Enrollment
6750
Start Date
2023-08-07
Completion Date
2026-07-31
Last Updated
2025-12-19
Healthy Volunteers
No
Conditions
Interventions
Targeted BEP based on baseline nutritional status
In Arm 2 (targeted BEP based on baseline nutritional status), in addition to the standard of care, participants will receive BEP supplements if their baseline BMI is less than 18.5 or their baseline mid-upper arm circumference is less than 23 cm.
Targeted BEP based on baseline nutritional status and monthly GWG monitoring
In Arm 3 (targeted BEP based on baseline nutritional status and monthly GWG monitoring), in addition to the standard of care, participants will receive BEP supplements if their baseline BMI is less than 18.5 or their baseline mid-upper arm circumference is less than 23 cm; participants with an inadequate GWG at a monthly follow-up visit will receive additional BEP supplements.
Universal BEP
In Arm 4 (universal BEP), all participants will receive BEP supplements from baseline through the end of pregnancy.
Locations (1)
Addis Continental Institute of Public Health (ACIPH)
Addis Ababa, Addis Ababa, Ethiopia