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ACTIVE NOT RECRUITING
NCT06126341

A Study to Identify Barriers to Cellular Therapies for People With Plasma Cell Disorders

Sponsor: Memorial Sloan Kettering Cancer Center

View on ClinicalTrials.gov

Summary

This is an observational study that will include both participants with relapsed/refractory Multiple Myeloma and their doctors. The purpose of this study is to gather information about the use of hematopoietic cell transplantation/HCT and B-cell maturation antigen /BCMS targeted chimeric antigen receptor/CAR autologous T-cell therapy.

Official title: Prospective Multi-Center Study to Identify Barriers to Cellular Therapies in Patients With Plasma Cell Disorders PROACT PCD

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

49

Start Date

2023-11-03

Completion Date

2029-05-03

Last Updated

2026-02-19

Healthy Volunteers

No

Interventions

OTHER

Lecture on the role of cellular therapies in relapse/refractory multiple myeloma/RRMM

Physician investigators will review a lecture on the role of cellular therapies in relapse/refractory multiple myeloma/RRMM that discusses current information in regards to available cellular therapies in RRMM and a proposed treatment algorithm.

BEHAVIORAL

Hospital Anxiety and Depression Scale

Depression and anxiety will be assessed using the Hospital Anxiety and Depression Scale (HADS), a 14-item self-rated questionnaire

BEHAVIORAL

Duke-UNC Functional Social Support Questionnaire

A 14-item, self-administered, multidimensional, functional social support questionnaire has been reduced to an 11 items to a brief and easy-to-complete two-scale, eight-item functional social support instrument.

BEHAVIORAL

Distress Thermometer

The Distress Thermometer is a single-item visual analog scale used to screen cancer patients for the presence of psychological distress

BEHAVIORAL

FACT-BMT

The FACT-BMT Version 4.0 is a 37 item self-report questionnaire that measures the effect of cancer on Quality of Life domains

BEHAVIORAL

Psychosocial Assessments of Candidates for Transplantation

The PACT scale is a single page 10-item rating scale with high inter-rater reliability that has been used extensively in solid organ transplantation

Locations (8)

Hartford Healthcare Alliance

Hartford, Connecticut, United States

Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

Montvale, New Jersey, United States

Memorial Sloan Kettering Commack

Commack, New York, United States

Memorial Sloan Kettering Westchester

Harrison, New York, United States

Memorial Sloan Kettering Cancer Center

New York, New York, United States

Memorial Sloan Kettering Nassau

Uniondale, New York, United States