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taVNS for Letter Learning in Dyslexia
Sponsor: University of Florida
Summary
This is a pilot study to establish feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) for improving letter-learning in adolescents with dyslexia. The main goals of the study are to 1) evaluate whether children in this age range will tolerate low level stimulation over the course of multiple sessions, 2) determine whether low level taVNS improves novel letter learning in dyslexia, and 3) evaluate the effect of low level taVNS on the brain's response to letters. Participants will complete fMRI before training, immediately after training, and a few weeks after training ends. Training will consist of six 30-minute lessons during which participants will learn novel letter-sound relationships while receiving either active or sham taVNS. Researchers will compare stimulation conditions to determine effect of this device on learning and neural plasticity.
Official title: Effect of Non-invasive Vagus Nerve Stimulation on Letter Learning in Dyslexia
Key Details
Gender
All
Age Range
10 Years - 12 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-09-01
Completion Date
2029-09-01
Last Updated
2026-05-28
Healthy Volunteers
Yes
Conditions
Interventions
active taVNS
low level stimulation to the auricular branch of the vagus nerve
sham taVNS
device placed with no current administered
Locations (1)
University of Florida
Gainesville, Florida, United States